Lack of cash is a major cause of depression. Rent is very expensive in CA. Some don't make enough money. Others can't control spending and live within their means.
I have similar types of social problem. I'm from Washington State and have lived in CA for 20 years. Fish oil and Glutamine seem to have taken care of my mild depression.
It's seems impossible to meet people you would want to have around. Your busy at work then you get off and have to do some exercise you just don't have any time to meet anyone. Plus they likely are married or just not interested in my type. Recently I have been trying online dating. It seems to be working. I get contacted every day by new women. If I want to go out with one or do some activity like roller blading I just reply. Even if I decide to not go out it's good to know I can if I want. Because I'm a man I don't have to worry about being raped. If I was a female I might be concerned.
One of my friends in Washington was always dating off the computer and I thought he was a social path. I thought it was weird. He lived in a small town so he would have to drive for hundreds of miles. He ended up married to a Russian.