For example Histolytica is described in the big best books to very often actually give lots of micro perforation of bowel wall...the same books says this will cause things inside bowel to leak into other parts of body...it is quite amazing how body for years and years even can withstand this if not leak too big...of course person will feel horrible
Body is amazing at cleaing out anything it do not want...but in such leakege the body has to work hard hard hard....
of course no matter type of cleansing in such case will be just crap....In best case it will cause a little very short term improvement because many cleanses causes diharea and just quickly flush out all in bowel...then just less material that can leak thorugh micro damage in micro wall...but so called cleanisng in such cases is more likely to do harm than good...and it will not remove the cause.