"coumadin does? no. it is not even an actual blood thinner; it inhibits blood clotting, which is what it does in rats to kill them. it is just that we are bigger and it takes us longer to die and we don't use as high of doses, relatively."
OK, "blood thinner" is the layperson's term. I would be interested in what you consider an "actual" blood thinner.
You're absolutely correct in that DOSAGE per body weight is the critical factor in pharmacologic safety. That was my point. Even water is toxic in high enough doses. It is from THERAPEUTIC doses that we gain benefit with a very good safety margin.
I'm sorry to digress from the original topic and I apologize.