hi dee, i don't use enemas. i have them all in the tissue surrounding my anus and rectum-i dont go there. but you do need to take milk thistle for your live health-cause the prazi wrenches it. i take it as a supplement when i'm not on my prazi & quin hao treatment. i begin my 14 day treatment starting on the full moon of every month. on 3 days, off 7 back on for 3 more. i do my quin hao every sunday.