Re: Minimalist Yeast Abatement Protocol

We're not just talking about a few acetaldehyde molecules here and there. To put things into perspective let's see what happens in the worst case scenario if budding yeast in the gut gets a hold of and metabolizes an entire teaspoon of Sugar (sucrose).

In one teaspoon of sugar:

1 tsp sucrose X 4 g / tsp X 1 mol / 342.3 g X 6.02 x 10^23 molecules / mol

equals about 7 x 10^21 molecules of sucrose.

There is one molecule of glucose for each molecule of sucrose and each molecule of glucose yields two molecules of pyruvate which can be metabolized by pyruvate decarboxylase in yeast into one molecule of acetaldehyde and one molecule of carbon dioxide (the gas/bloating symptom).

1 tsp sucrose = 7 x 10^21 X 1/1 X 2/1 X 1/1 = 14,000,000,000,000,000,000,000

There are potentially 14 sextillion molecules of acetaldehyde (about 1 gram) that can be released from Candida Albicans yeast cells for each teaspoon of Sugar that they are fed! Twenty-five percent of the ingested Sugar may emerge from the reaction as a harmful substance. Each and every one of these acetaldehyde molecules that isn't apprehended can cause damage to the body in any number of different ways.

The single dose Wondro formula uses about 1/2 teaspoon (5 grams) of elemental sulfur. Assuming that the heating process combines all of the available sulfur into the unsaturated fatty acid bonds in the flax oil, then

5 g S X 1 mol / 32.065 g X 6.02 x 10^23 atoms / mol

equals about 94 x 10^21 or 94 sextillion atoms of "combined" sulfur in the resulting compound.

About 50% of these (47 sextillion) may be available for acetaldehyde binding. This supposition is supported by a naturally occurring process in the body in the pyruvate dehydrogenase reaction portion of the citric acid cycle where acetyl-coenzyme A is formed:





http://www.brookscole.com/chemistry_d/templates/student_resources/shared_reso...


As an intermediate step in this reaction, acetaldehyde breaks into the disulfide bond in lipoic acid. This may be very similar to what happens to the sulfurated fatty acids in flax oil when they encounter acetaldehyde in the gut.

[Question: Would the second -SH structure be capable of assimilating another acetaldehyde or not?]

It is important to note here that although the body does indeed use the acetaldehyde configuration in the production of acetyl-coenzyme A, it only does so when acetaldehyde is "immobilized" safely within an enzyme. It doesn't allow it to float freely in the cellular milieu. The intent of a good acetaldehyde scavenger, then, would be to similarly immobilize rogue molecules of acetaldehyde released in unexpected locales.

As a comparison the suggested Wondro alternative protocol uses two 500 mg capsules (1 gram) of N-acetyl-L-cysteine which may yield up to:

1 g NAC X 1 mol / 163.19 g X 6.02 x 10^23 molecules / mol

equals about 3.7 x 10^21 or 3.7 sextillion atoms of sulfur in the emulsion, since there is one sulfur atom per molecule of NAC with all of these potentially available for acetaldehyde binding.

Based on these calculations the Wondro formulation would be at least 10 times as potent an acetaldehyde scavenger as the NAC emulsion but the NAC emulsion is easier to make (no heating) and to take (odorless).
Tweet