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~RN #142060
12 y
7,060
† C †
I don't know why "everyone" should do that but in doing so for my
own edification I found this:
http://myeloma.org/ArticlePage.action?articleId=1560
.....Multiple
myeloma is a cancer of the bone marrow caused by the uncontrolled growth of
plasma cells. Manufactured in the bone marrow, plasma cells are a critical part
of the body’s immune system. In adults, the most active bone marrow is
concentrated in the pelvis, spine, and skull, as well as in the long bones of
the arms and legs. Normally, plasma cells make up less than 5 percent of the
cells in the bone marrow, but individuals with myeloma have a significantly
higher concentration of plasma cells in their bone marrow – greater than 10
percent and sometimes more than 90 percent. The danger associated with this high
number of plasma cells stems from the fact that they are malignant and can
invade and destroy the surrounding bone and displace the normal blood-producing
cells in the marrow. The increased malignant plasma cells can actually dissolve
bone, weakening areas of the skeleton and causing a severe osteoporosis-like
appearance to the bones. The displacement of normal marrow causes anemia and
reduced levels of white blood cells and platelets.
No
single factor has been consistently associated with multiple myeloma. Overall it
appears that certain occupations, as well as exposure to certain chemicals or
radiation, can sometimes cause the disease in predisposed individuals. The
diversity of possible exposures and genetic susceptibility factors make proof
difficult. Recently, researchers have proposed infection, particularly viral
infection, as a causal or trigger factor. Several studies have linked multiple
myeloma to HIV, hepatitis, herpes virus infections (especially herpes virus 8),
Epstein Barr Virus (EBV), as well as new “stealth adapted” viruses such as
mutated cytomegalovirus (CMV). The significance of these viruses with regard to
multiple myeloma remains to be fully explored.
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I have none of the "linked" diseases and they are only a
"trigger factor." MM is not a virus. I learned nothing
new.
The International Myeloma Foundation is on the forefront of MM study.
Here is more information on MM statistics for the same site:
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