Hello balverie and thanks for your good advice (hopefully)! I see your message was dated 8 years ago when you had just started your regime of different medications to treat your leaky gut. May I ask how you made out? Was it successful? I just ordered your prescribed advice and will be starting it this week. Why the big difference in strength of msm? You mentioned 2000 to 10000. My body can hardly tolerate anything I try but I am so disgusted that I am going to go for it. I do hope it helped you! Please let me know! Should I treat candida after I finish your advice? Difficult to treat it now because, as I mentioned, I cannot tolerate probiotics or acidophalus. Hope to hear from you or anyone else sharing some helpful advice on the subject.