Thank you all for the recommendation of California Baby shampoo, which I found at Target. It is expensive, but I can't believe how much better my hands are now. I'd like to say they are completely cured, but I'm afraid of jinxing it. After several years of living with itchy, oozing bubbles and horribly painful cracks and fissues, it's nice to look down and see healthy skin again. I am going to try someone else's suggestion of gloves when I shower, though, b/c after 6 weeks of using only CB shampoo, I am in desperate need of a good conditioning. But hey, 6 weeks isn't bad! I will continue using CB shampoo, because while I hate the price (between $17 and $18 per bottle), and I don't like the odd smell -- yes, fragrance-free things still have their own odd natural smell -- these things are a tiny price to pay for healthy hands. I'd like to let you all know that before using CB shampoo I also noticed that if I didn't use gloves on my hand for housework - even a quick swipe at the counters with a chemical - I started to get the familiar itch. A soaking in vinegar seems to calm them down and stop the bubbles in their tracks, but why go through all of that? I use gloves faithfully now. So between these two things, I think I've got a handle on what my problems were. Thanks again to everybody on this forum that weighed in on what they've tried.