Re: The War against Dientamoeba fragilis
Yahia,
Hmmm... These are very interesting properties associated with protozoal infections.
Firstly, I'm a chemist, studying nanoscience, so I have some scientific background. It is a strange thing to say that the redox potential for a whole cell is reduced, but then I'm only a novice microbiologist. When we speak of redox potential, we normally are talking about half-cell reactions, which denote the ease of addition or removal of electrons to a particular chemical species. I suppose it makes sense that this measure of electron affinity could be transferred to measure the redox potential on the surface of an epithelial cell, and this is what you speak of. I'd like to see that paper if you have a reference. ;)
I didn't think that D. Fragilis or B. Homonis were supposed to be found anywhere besides the intestinal lumen. Entamoeba hystolitica being found in the connective tissue is a frightening prospect. So what is your idea? Would you want to try something that inhibits that particular enzyme? See how well those little bastards hang on then? Send me this paper too, if you have the chance.
Thanks for your thoughts. I'll be back with more soon, and keep up the good fight!
-BaDnOn