Re: more
Hello John,
No, I think you are missing the fact that if the vitamin D receptors were really blocked and the whole process was spinning out of control a person would quickly die due to excess calcium in the blood.
Since this is not happening, I have to assume that whatever you think is blocking the vitamin D receptors isn't really blocking them.
However, if you limited the raw material (D3) you could cause the body to feed off of its bone mass...
Also, isn't it the vitamin D receptors that trigger the production of 1.25 D? If you have excess 1.25 D in the blood perhaps the receptors are working fine.
On top of that I believe that recent studies have revealed that it appears that every cell in the body may have a vitamin D receptor, so it would be very difficult to block every cell in the body all at once.
The studies I have reviewed indicate that high 1.25 D levels in the blood are an indication that calcium is not being absorbed. Once you get the calcium under control, the 1.25 blood levels settle down. I don't believe there is a test for cellular 1.25 D or 25 D levels, but that would be very interesting.
Tom