Thank You for your advice, I too think that's what happened, the Candida began to resist the Diflucan. It's amazing how doctors think that the Diflucan is the answer, and if it doesn't work, then there is no cure. They don't even suggest the no-sugar diet. I told my Lyme doctor that I was going to do that now, he is wonderful at being a doctor of Lyme but that's it. He said he didn't think that "having a plate of spaghetti would do me any harm." No wonder it took so long for me to figure out what was wrong with me.