Yep..I'm beginning to think that Vit C is about the most important thing to support the Iodine or I guess help with the detox that Iodine starts, and I take it daily between 3-10 grams and it works great. It sure took care of that stiffness and cramping in my calf, and probably my legs since they would get crampy at night sometimes too. It also took care of that weird colon pain that would just come on and shoot right thru me..ugg..so glad that is gone!