My experience from having been around labs is that chemically reagent pure is ultra pure. It has to be or it screws up the lab test/experiment. In fact, many lab tests demand a higher purity of product than does USP rating. The USP rating just means someone paid a fee. It doesn't ensure that the maximum purity is being met. In fact, it only ensures that a minimum purity that is designated has been met. Example: They sell distilled water in the grocery store for human consumption. It has only been distilled once and the quality can vary alot. But distilled water used in hospital labs for lab tests (but not rated for human consumption) is triple distilled-- meaning a much purer product. So, if you find a company selling Lugol's rated "reagent pure" it is just as safe to take as being rated USP. If the USP stuff is a little thicker some of the times, I would be concerned that the USP wasn't as pure as it's cousin, the reagent pure.