I was informed that Dr. Catherine Orsoni has retired. Yes, she wrote a book on using trace elements to treat cataract, although I don't have it. I was told her work on trace elements is being continued by Dr. Boris Rysanek, but his profile says he is a cataract surgeon and a retinal specialist. Possibly, he is using trace elements to treat retinal diseases, but probably not cataract.
Of course, over the last century, many people have indeed been working hard to treat cataract, but if you look at who they were, nearly all of them were biochemical researchers and none were ophthalmologists. The only exceptions I know of are the following:
Dr. William Luftig who practised light therapy for cataract from 1914 to 1958, was originally an 'orthodox' ophthalmologist from Berlin University. He states that, using white light and colored light sources focused onto closed eyelids by a system of crystal glass reflectors and lenses situated one or two meters away in a darkened room, within the span of a few weeks, he was always able to get rid of cataract symptoms and restore them to a satisfactory level of visual function. He also documented the regression of their opacities by the standard slit-lamp ophthalmoscope. He said he even got some improvement in cataract patients who 'could only perceive the difference between light and dark'. He further stated that all his attempts to publish case studies in peer-reviewed ophthalmology journals were rejected, and that the only time his work was recognized by other ophthalmologists and eye surgeons was when they sought him out to avoid surgery on their own eyes.
Robert Brooks-Simpkins, who practised a similar form of light therapy for cataract in the 1970s, was also an eye doctor, also documented regression of cataract opacities, and was likewise ignored.
Dr. Stanley Evans was an eye doctor who treated cataract for 40 years via a nutritional approach in the UK and Africa, who published many books now all out of print, and who passed away in 2010, was also completely ignored by the eye profession.
But all the great achievements in reversing cataract with eye drops over the last 50 years, in the lab or in animal models, were made by biochemists with no participation from the eye profession or from pharmaceutical companies whatsoever. Biochemists do not have approval to run clinical trials, and since all of them were so far ignored by the eye profession which is the only organization approved to run clinical trials, this is why we do not have alternatives to surgery today.
Recently, the advent of lanosterol and other sterols has changed this situation slightly, but sterols only stabilize alpha-crystallin, they don't free it up. So I say that sterols are far less able to reverse cataract than AGE-crystallin crosslink breakers, which do free up alpha-crystallin. One was already shown (by biochemists) to restore free alpha-crystallin in 2008, which is why I am confident to say that this class of compounds could reverse even advanced nuclear cataract.