Re: Anybody's hypo worse after eating wheat/dairy?

Wow, interesting discussion... if a little misinformed.

Okay Celiac Sprue is an autoimmune disease that manifest as a humoral immune attack on the small intestine instigated by the presence of a transglutaminase/gluten-peptide fragment in the small bowel. It is mediated by an IgA/IgG immunological pathway, not an "allergic" IgE pathway. The disease has a definite genetic component, as evident by numerous HLA typing studies. The immune attack on the small bowel can be histologically demonstrated by a biopsy and the damage ceases and heals completely on a gluten-free diet. This is the most convincing evidence that the disease is limited to an autoimmune attack triggered by the gluten of wheat, barley, rye, and possibly oats (plus their relatives). Celiacs can safely eat a number of grains, including processed grains like white rice with no problems.

The coincidence of Celiac sprue and thyroiditis is not a grand Conspiracy of some chemical or bacteria. Celiac sprue is one of the most underdiagnosed condition for a variety of reasons, but it is estimated to affect close to one percent of the population (in the US). It conincides with Thyroiditis because they both represent a break in central tolerance. It is known that when a single autoimmune antibody is present there are usually others. The induction of one autoimmune process can lead to a general upregulation of autoimmune processes and is why most people who develop autoimmune conditions tend to exhibit them in close succession.

Conclusion, autoimmune disease is a problem of bad genetic luck coupled with an environmental stressor that sets off an immune response that can't be shut down. Those reactions in turn cascade to others.

One final note: The assertation that Mono-Sodium-Glutamat (Natrium Glutamat) is somehow unnatural is pure bull. Mono-Sodium-Glutamat (Natrium Glutamat) is produced naturally by a bacteria (Corynebacterium glutamicum if I remember correctly), it is just harvested in vast quantities for use. I am not advocating the use of Mono-Sodium-Glutamat (Natrium Glutamat) (I have never utilized or consumed it... oh yeah, and I have celiac sprue and thyroiditis, along with chronic autoimmune gastritis), just pointing out that the statement about the "nature" of MSG is very inaccurate. Tweet