I have done urine therapy, which I give by injection in my butt, taught to me by a very experienced MD, who thinks outside the box. He also told me that I must take meds for hypothyroidsm, since I was way under the required levels. So whilst on naturthroid(not synthetic but natural source of thyroxine T3 and T4) I was also receiving from him urine injections. He never ever once indicated that in order to do this treatment I should go off the medication, in the fact the opposite was true. Whenever I am feeling down, or have caught some sort of virus etc. I administer the injections of UT. Hope this helps somewhat.