I have adrenal fatigue also(diagnosed and treated using cortef in varying amounts). I was just curious how this has effected(with and without treatment)your weight? At first I lost weight, now I've gained an inappropriate amount for what I eat. I do mostly lo-carb. I seem to have swelling around my lower legs. I wonder if this is thyroid(I take 150mg Armour, and up to 20 of cytomel a day), or if this is b/c adrenals. Any thoughts since you seem to have quite a history of experience with this. Also sometimes when I take my cortef I become quite nauseated, what could that mean? Thanks