Are you on the diet? If not, that is where I would start. Also, check out the parasite forum. From reading over there... I guess parasites LOVE probiotics and that is why sometimes people are unable to take them? I'm begining to suspect parasites as well. I have major joint and muscle pain and numbness too. I guess they both come hand in hand ( parasites and candida) and many symptoms did improve on the diet and supplements. I'm also getting my blood sent out *again* to test for Lyme.