If you are very toxic and want to start slow, start with only 1 or 2 tbsp in little juice. It acts as a laxative. It is recommende that u do it early in morning, when there is no food in stomach and intestines.
After a while you can build up your dosage to 4 tbsp ( ~60ml). Very big ppl can take upto 5 tbsp (~75ml) with juice. At this amount it acts as purgative.
It is a liver, bowel, parasite cleanse. You can do the cleanse once evrey 2 weeks. If you are very sick you can do it weekly. It helps in moving the gunk out of the intestines and you should see a reduction in size of belly. If you have a pot belly.
I have also read that taking a tsp or CO everyday at bedtime helps in emilimating toxins. This helps with IBS, arthritis etc. I dont take it everyday though.