Sometimes I apply some neosporin that has numbing agent in it to the sore area, especially before going to bed if it is particularly bad, but I hate using anything with petroleum products in it, so that is rare.
Recently I have tried tea tree oil, since it seemed like all the moisture was irritating the area. It burned on its own for a bit, then seemed to heal the owee zone.
The extra virgin olive oil I use to lube the enema tip seems to soothe. Maybe try that one. Cannot hurt.