I really don't know what kind of Colon Cleanse you were doing, but I've done cleanes with herb pills and that's all they did was make me poop a lot too. I've been on this three days, and already I see results! I have poop that comes out and it is shaped like my intestine just like the pics on this website. I can tell it's actually scrapping the walls of my colon. I've tried the shakes before, but it didn't work, but what I found out is that you must take the shakes on an empty stomach then eat an hour later. That made a huge difference in my results, and of course lots of water is necessary. So in a nutshell, yes it should. The Psyllium actually will physically scrape you out, not just make you poop more, like a laxative or something. Just pooping more won't take away mucoid plaque, you gotta scrape it out with fiber. The benonite plays a big role too, but I'm not sure how. I know it absorbes toxins, but I really can't explain it anatomically, if you kow what I mean. Anyway....Just wondering: you say you eat healthy. what are you eating?