Re: Some basic chemistry and biology

I'm not arguing anything you said, I'm just making comments.

Trans fats takes the place of other fatty acids and disrupt some processes, don't they?

H+ ions can bind with histidine, thus disturbing many enzymes (allogenic competition with their mineral cofactors I believe?) and hemoglobin's affinity for oxygen.

Ammonia is a good buffer, but it uses up our stores of glutamine, and isn't ammonia toxic?

Isn't there limits to how much CO3- the pancreas can make?



There is something called the potential renal acid load (PRAL).

""""Therefore, it appears to us that the average net base production of -88 mEq/d (ie, the absolute figure) calculated by Sebastian et al may be too high for Stone Age persons with high protein intakes. This is also confirmed if the average PRAL and NEAP are calculated from the average nutrient intakes of Stone Age persons as recently published by Eaton and Eaton (9). Using their figures on daily nutrient intakes, we estimated a negative PRAL of -39 mEq/d, leading to an NEAP of 22 mEq/d, which is markedly lower than current net acid excretion (64 mEq) in the United States (Table 1Go)."""" [...]

""""Reasons for the historical shift from negative to positive PRAL are not only the displacement of alkali-rich plant foods in the ancestral diet by cereal grains and nutrient-poor foods in the temporary diet but also the modern processing and preparation of foods, which lead to considerable losses of base-forming nutrients such as potassium and magnesium.""""

Taken from: http://www.ajcn.org/cgi/content/full/78/4/802 Tweet