well the mole turns black, that black hardens like a scab and you just wait for it to fall off. at least that's what happened to mine, and to the girl who told me about using ACV. The skin around the mole gets irritated but, I have learned to put vaseline around the mole so the ACV doesn't have contact with the skin. That's all that happened. the smaller mole the scab came off already. But the big mole is still black and hard, I think it is going to take time for that one to fall off only because of the thickness, I also keep it covered with a bandaid for work, that one is just under the jaw bone so it is no big deal. while I am home I leave it uncovered so air could get to it. Try it on one , see what happens. let me know