Re: Update
With such a serious situation in play I would not be messing around too much with supplements without some professional assistance and appropriate medical tests.
Have you gotten a nice sex hormone panel? If you have lots of symptoms of adrenal insufficiency/fatigue and your doctor is not likely to prescribe hydrocortisone or similar, I'd include pregnenolone in the blood test. Many people can get that at directlabs.com
What dose of Preg did you try? Plenty of chemically sensitive people struggle to tolerate even 10mg x2 /day. That dose won't likely be even close to enough to fully compensate for HC in a person that needs the medication.
How is your Free T3 and other thyroid hormone test results? If on the low side, ever try selenium?
Getting some magnesium, appropriate amino acids, maybe methylation support--B12, folate, etc?
Hopefully others will have thoughts for you.