I am having experience with it. I have chronic candida in addition to heavy metal poisoning. Many of the metals are high, but my lead and mercury levels are off the chart. I've done 20 rounds of IV chelation with Ca EDTA and DMPS. We do the Ca EDTA all of the chelations, and add the DMPS every other chelation. In my opinion It does seem to stir up the yeast which has been a chronic problem prior to discovering the heavy metal poisoning. Part way through the chelation I went back on the McCombs plan again for the candida. I have now increased my anti fungal dosage of Candida Force, or Formula SF-722 from the 5 pills 3 times a day, to 5 pills 4 or 5 times per day. I am currently on the "break" for a few weeks after the 1st 20 rounds of IV chelation. We have run another metals test, and I am waiting for the results, but I am expecting at least another round of 20. I am determined to get this out of my system the fastest way possible. I want my life back.