I understand! There is much contradictory info on the internet. I decided to go by Dr. Uzzi Reiss, a well-known women's doctor in Beverly Hills, with all his years of experience. He has 2 books on Amazon. Anyway, in his experience, the pregnenolone did not cause a rise in all the other hormones like so many say on the internet, and he treats his patients with hormone lab testing. The messages about copper I found very interesting, I read some of those links. The Wilson site does indeed talk about severe changes with a Merena, as it has copper. I hope you read those links sent by others as if you have a copper toxicity going on, there are things you can do to balance it. Anyway, I am not pushing what helped me, just letting you know about it.