Re: A "Wormy" Apple A Day Keeps the Doctor Away!

James,
Candida Ralated Complex isn't a syndrome caused by the morphogenesis from yeast to fungus.
There are thousands of people with symptoms affecting remote organs and systems caused by metabolites expelled by an excess of the "commensal" form of candida albicans in the intestines. In these people the conditions haven't been created to allow candida albicans to morph to a more virulent and invasive state. In a few words, to be symptomatic it isn't necessary the transition from a buddy cell to mycelia.
The single cell produces the same amount of toxic metabolites that the more virulent form does. They are the same organism with a phenotype change only. The fungal form allows candida albicans translocation and epithelial cell penetration converting it in a more virulent form.
CRC is a syndrome caused by the by-products and wastes candida albicans produces. All of this added to the local symptoms caused by the yeast presence on the infected tissues such as inflammation, burning, itching, discomfort, etc.

In my view, there are other cases where factors such as antibiotics have altered the mechanism that avoids the morphogenesis and dissemination allowing candida albicans to sense it and to switch to fungus. Scientific are still no clear what exact mechanism triggers this transition. There are studies pointing to Ph, bacteria, change in temperature, and even candida albicans ability of sensing when the host defenses are low. It is clear the friendly bacterial flora has a protective role avoiding massive yeast colonization in the gut, specially protecting against the morphogenesis.

Of curse, candida sufferers who have been victims of the candida albicans morphogenesis in the intestines have a more complex and difficult case to treat. The fungal form penetrates the epithelial gut cells causing inflammation of the intestinal wall triggering permeability and a leaky gut.

The main point is there are many people suffering this syndrome who don't complaint of intestinal symptoms, still they are affected by a chronic presence of the yeast in the tissues and its remote systemic effects.
The cause of this syndrome is an immune tolerance to the yeast that builds up as a results of its presence in our tissues in enough amount for enough time.
In the intestines, the presence of an antagonistic and competitive balanced friendly flora inhibits and control yeast dissemination until this last resource be disrupted by antibiotics or any other offender to our native flora.

People who develops an intestinal yeast overgrowth have an immune tolerance state sets up waiting for a trigger such as antibiotics to experience a severe intestinal yeast colonization. Remember, there are people who takes long term broad spectrum antibiotics and never develop candida related complex. Those people are who have an active immune response to candida albicans.




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