Have you looked into pyroluria and other copper related disorders which prevent adrenal recovery? If you're a "copperhead"(estrogen overload, water problems and more offenses) you're heavily deprived many nutrients due to excessive copper in which case the release valve for toxins is shut off and you will continue to accumulate them at an alarming rate, causing neurotransmitter and hormonal problems. check out low or high histamine,each having very different supplement needs. The beauty of it's discovery for me? Reduction of problems within the first day.
Histadelia
histapenia
Pyroluria
This info still relates to having gut dysbiosis which requires further help, but Im grateful for less suffering and the
possibility of recovery.