Some people have success in micromanaging their body's systems as you are doing with your intestinal flora. I've found that using a program of cleanses, Clark's in my case, has worked better. It will be important to you to find out the underlying causes of your body's dysfunction. You already know about the leaky gut (and heavy metals) but you don't have a clear idea of why you have this.
I've used Epsom Salts sweat baths and it may help you sweat out sulfur conjugated toxins.