A Rife machine is basically a sound generator. It has two different types of sound. One is like a dot. Short quick sound. One is like a dash which is called a sweep sound. The sweep is more 'stretched' and it varies in pitch.
The idea being that everything in physicality is composed of sound vibration including harmful microbes. The frequency generating rife technolgy produces a sound that is the antithesis of the particluar microbe which disintegrates it. Since good bacteria does not live in harmony with bad bacteria they do not occupy the same sound field. Thus the good bacteria are not harmed since they exist on a different plane of vibration.
My rife machne has an 'amplifier' of the sound which projects the frequency deeper into the body using an argon light bulb. The bulb also flashes in dots and dashes as the sounds are emitted. The bulb makes the unit more expensive but more effective too. Also my unit is programmed with all the frequencies. So if I need any particular sounds say for smallpox I just set the machine for that setting and hit start. Many machines require settings to be adjusted before usage. My unit is more automatic.