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I broadly recognize two types of cataract.
1. Cataract due to clumping of lens crystallins.
2. Cataract due to covalent bonding of lens crystallins with advanced glycation endproducts (AGEs), or xanthurenic acid and its derivatives.
The main AGEs in the human lens responsible for binding crystallin and causing cataract are: imidazolone, argpyrimidine, carboxymethyllysine and pentosidine. Most of these AGEs and the resulting AGE-crystallin complexes are colored yellow or brown pigments so the cataractous lens takes on a yellow or brown color. Some of these AGEs are fluorescent, so the cataractous lens fluoresces when exposed to light of certain wavelengths.
Now many of you will have heard by now that there will be trials of lanosterol eye drops to treat senile cataract. It seems to me however that lanosterol will only address the first type of cataract due to simple clumping of crystallin. For the second type, we would need an eye drop containing an "AGE breaker" which is able to release the crystallin from its shackles to the AGEs and xanthurenic acid.
Around the year 2000, research was carried out in Japan on aminoguanidine (AG) to explore its AGE-breaker potential in cataract. Improvement in lens clarity was obtained, but the effect was only temporary. Now, a new AGE-breaker, more powerful than aminoguanidine, and which works on crystallin, has been discovered in Japan - water caltrop extract. Please see the following link:
http://www.toukastress.jp/webj/article/2015/GS15-13.pdf
This extract is made from water caltrop, an aquatic water plant commonly known as Chinese water chestnut, which is used in Chinese cuisine. In Southeast Asia, water chestnuts are also sometimes eaten raw, which is risky as the plants can harbor flukes or parasites that can infect humans with lethal consequences if untreated. However, we do not expect any such problems with the extract of water caltrops.
And my point here is that we urgently need for a company to make sterile eye drops from water caltrop to clear the lens from age-related cataract of the second and most insidious type, which is due to binding of lens crystallins to AGEs. If you read the above link, it seems like this would work.
I would like to suggest a second step after using AGE-breaker eyedrops.
The previous Japanese experiments with aminoguanidine or organic germanium (germanium sesquioxide) were only able to achieve a temporary restoration of lens clarity. This is not surprising because the AGEs were not removed from the lens - they merely recombined with the lens proteins (crystallins) when the experiment was stopped, and the lens became opaque again.
The growth of a cataract is largely due to the failure of the pump at the back of the lens, the so-called Na+/K+-ATPase pump, whereby the lens acquires nourishment from the aqueous humor and discharges waste products back into it. Were we to free up the crystallins from the shackles of the AGEs with eyedrops, preferably containing nanoparticles of AGE-breakers like water chestnut extract, we would still have to remove the AGEs from the lens. I believe this could be done by reactivating the lens pump - in other words, by re-establishing circulation within the lens - by consuming Chinese or Japanese traditional herbal medicines such as "Hachimijiogan". I found a reference on the Net stating that "Hachimijiogan" ("Ba Wei Di Huang Wan" in TCM) does reactivate the lens pump. Alone, oral consumption of these herbals might not have much effect in cataract, but combined with the use of AGE-breaker eyedrops, there may well be significant cataract reversal and permanent restoration of lens clarity.
It's been a long time since I posted here, and now I can barely see the screen due to the cataracts.
Some of you may remember, several years ago, I testified that top eye professionals had told me straight:
"We get most of our income from cataract surgery, so we don't want to cure cataracts. We know there are ways of treating them, but we will never allow them to replace surgery".
It was this statement that prevented me, and prevents me even now, from having cataract surgery.
As it turns out, there are several new methods coming soon that will clear cataracts away without surgery.
I cannot discuss them in a public forum like this, for fear that they would be suppressed. But still, I feel it my duty to at least let other cataract sufferers know that there are people who care, and want to do something about it.
Actually, cataracts are just another example of how "modern medicine" approaches disease. "Modern medicine" treats diseases, not people. People with diseases are no longer "people", they are "cases" or "case studies". Doctors view the "cases" as lumps of flesh and organs containing defective parts that just have to be cut out or killed off, even if that leaves the person with a functional disability.
And then they proudly go on to tell other doctors how they treated their "cases" through medical journals - the Internet is teeming with their arrogant reports. These modern medical so-called "treatments" cause a great deal of human suffering which could have been avoided by the real cures out there - you name it: heart by-passes, chemotherapy, dialysis...The list goes on and on. No attempt is made to restore the function of the human body - only to cut the defective parts out surgically, or administer drugs with life-threatening side-effects. Today, modern medicine is so deeply entrenched that the world population takes all this for granted, and never questions it. But you can see the results of this monstrous, barbaric policy for yourself. For example, how many people do you see around you every day in wheelchairs? It's not because they can't be helped. As you can see from all the research reports on the Internet, the technology exists today to cure practically every human disease. But none of it is getting to the people who need it because it's just bad business.
Conclusion: Since the eye profession is a "business", and curing people is bad business, why would we expect the eye profession to be any different from the rest of the medical profession?
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