Cholesterol coagulation, cholesterol crystals nucleation time

Cholesterol is not a fat but a solvent which is dissolved and kept in solution as a flowing liquid when there are adequate amounts of essential fatty acids. The melting point of cholesterol is 300 degrees F. When lecithin is present (a major component of bile), the melting point of cholesterol falls to 180 degrees but it is still insoluble. However, when the essential fatty acids linoleic and linolenic are present in sufficient quantity, the melting point of cholesterol falls to 32 degrees, which is below blood heat. Bile contains a proportion of these essential oils together with oleic fatty acids; the same component as olive oil. When bile is released into the gut in response to the flush potion and in the presence of Epson salts the cholesterol is prevented from being re-absorbed but the essential fatty acids are. Consequently without the correct mix of cholesterol and fatty acids the bile coagulates and solidifies forming balls of bile under certain circumstances. These balls of bile can be observed with true Gallstones and other liver congestion.



Experiments in a laboratory have demonstrated that bile from people without Gallstones takes about 15 days to form the nucleus of a gallstone. Bile of people with cholesterol gallstones, which, usually already contains cholesterol crystals has a nucleation time of about 3 days. Nucleation of cholesterol occurs far more rapidly from gallbladder bile of people with cholesterol Gallstones than from hepatic bile in the same person, even when hepatic bile samples are supersaturated with cholesterol. The addition of even small amounts of gallbladder bile to the hepatic bile samples causes rapid nucleation. Tweet