I started using Uriflow several months ago when my lithotrypsy was postponed. Within an hour and a half after the first capsule, the pain in my back had stopped. Another 2 1/2 hours after that, the first stone passed. A few days later, the second stone passed. At that point, I canceled the lithotrypsy altogether. The urologist was stunned and said there was no way I'd passed the biggest stone cuz it was too big. He called me in for a KUB x-ray and it showed the first two stones were, indeed, gone and the large one was showing signs of breaking down. About two weeks after that appointment, the large stone passed with only a few "ooch"es, not anything close to what I'd heard about passing stones. The first two had passed completely painlessly. I've continued taking Uriflow since I haven't had the other KUB to confirm the large stone is gone yet. My recommendation is to buy your Uriflow directly from the manufacturer's website. I think it's fresher. When I bought from another place, I had no results for several weeks. Two days after I bought directly from them, the large stone passed. Just make sure you get on their automatic monthly shipping thing. You can cancel anytime and it's MUCH cheaper than the single bottle price. Get that plan, even if you only intend to use one bottle. No sense spending all that extra money.