I have done about 12 flushes thus far. I have been working with a naturopath who got me started on them. He told me that once a week was definitely fine. I think you are absolutely correct that you alone know what your body can tolerate. I generally feel wiped out for a few days following a flush. I also have 3 kids to take care of and find that is hard to think of doing more than one every week or week and a half. But I keep on keeping on because when I see what is coming out I feel I need to keep going. It really is a powerful tool to help in regaining your health. THE LIVER IS SO IMPORTANT TO EVERY FUNCTION OF THE BODY. IT MUST PUT UP WITH ALL THE ENVIRONMENTAL POLLUTION, POOR FOOD CHOICES, CHEMICALS THAT ARE USED ETC, ETC, ETC. WE NEED TO TAKE CARE OF IT TO REMAIN HEALTHY!!!