How are your BM's right now? Are you at the very least going once per day? That is considered minimal. Ideally you should be going 2-3 times per day. When you start killing things off you want them to be eliminated from your body ASAP that's why bowel cleansing is recommended first. But if you have no problem using the bathroom I would say you'd be ok. I am using ParaGone myself right now. I'm on my second box and I love it! Good choice. I would say that yes ParaGone will help with cleansing out your colon but I would use something specifically for the colon. ParaGone increased my BM's in frequency and size and they turned really dark with lots of stringy mucoid plaque and yellow floating specks (no visible parasites or worms)! I was surprised. I've been cleansing my colon for a while too. Did CleanseSmart initially and then used B&P's for 7 weeks. Then just continued with psyllium 1 to 2 times per day and have been doing that since. A few months it's been. Good luck to you and Happy Thanksgiving!