I think it started to make me feel real sick after about 2 weeks of using 25 drops twice a day. You know I'm not sure whether it actually caused me to be sick by killing off all the good bacteria in my body or whether it woke up a latent virus inside of me and was in the process of destroying it. All I know is that using the product got me real sick for reasons I'm not sure of. One other thing is after stopping the dosage and eating yogurt for 2 days afterwards the sick feelings seem to be going away. This makes me wonder if I was in need of some good bacteria. I'd be curious to hear from others who have experience with this.