I have been taking Threelac at increased dosages for about a week now...started at 1, then 2, now 4 per day. I have had horrible leaky gut and candida and parasites for 25 years. A couple of months ago I let down my guard, tired of the meat and veggie diet of the last 4 years and had some barley malt sweetened goodies and some fruit and some things with white flour. AFter a month I developed a horrible case of gastritis, with reflux and esophagitis. I read that what goes on upstairs is caused by what is going on downstairs and started up with the Treelac again (tried it before but it constipated me). I am bloated and constipated off and on but the fungal Psoriasis on my arms and scalp is going away, same on my eyebrows, and I don't need the heavy antacid drugs anymore. I would love to buy a couple of cans at 50 bucks and hear some good news about the constipation and when it goes away. That is the only negative of the product. Email me at Stephr123@earthlink.net.