Even small amounts of vaginal creams are absorbed internally. I once used a very small amount of female hormone cream when I was experiencing menopause symptoms brought on by Depot Lupron injections (for treatment of endo)-- well even applying that topically to the outside vagina twice caused me to start having menstrual bleeding again! EVERYTHING we apply externally is absorbed into our bodies. Tc12 is reading from the insert that comes in these products, which unfortunately doesn't mean as much as human experience. Pharmaceutical companies won't acknowledge the negative side effects their poisons cause. Why would they--they're making trillions upon trillions!!