I've only been taking Iodine for almost 2 months so, I'm still a newbie but that describes what's been going on with me off and on these last few months.
I lose my appetite while I'm bloating. I've noticed I wake up hungry in the AM but then the bloating will develop during the day.
Also, I have gone through periods of extreme thirst. It means your body is trying to get you to take in more fluids in order to dilute the toxins that are flooding into your bloodstream. So, get your wife to drink, drink, drink! so to make sure the toxins don't just get reabsorbed into her tissues.
The bloating is definitely a detox symptom and i'm quite sure in the case of Iodine it's halogens. In my case, I belch a lot along with the discomfort/bloating since I've started Iodine. I remember bloating/belching when I used to swim so, I'm associating the same experience of bloat/belch during Iodine as a reaction to the halogens going into my blood stream.