I've always had slow detox problems ie. chemical & alcohol sensitivity, so I'm sure I do. My concern in seeking out intense detox regimens is just that it would be stressful/overwhelming on my body. I take a ton of vitamins/minerals always, but by intense regimen I mean MSM, diatomaceous earth, infrared sauna, etc. (Not that those specifically pertain to me or this condition just thinking what people tell me are detox/cleanse related).