Yes, I have had paradoxical reactions. I haven't taken most of the things you have taken, but when I take stimulating herbs I feel increased fatigue. I believe the reason this happens to me and possibly others is because our adrenal axis is already way over-stimulated. Generally, I actually think that in this state, the less herbs and supplements you take the better but certainly some people will need to supplement. For me so far, the things that have given me the most improvement are eating a diet high in carbohydrates with a proper amount of natural salt to hydrate the body, plenty of fruits and vegetables. I believe the high protein, high fat diet that many people follow to treat adrenal fatigue is actually the opposite of what you want in many cases (some cases could benefit from this, but they would certainly be feeling the benefit after a few months and not feeling worse). I have no idea if you are the same as me but this has been working for me. I follow the guidelines of Ayurveda.

Do you need more support for methylation and sulfation pathways in liver?

Joe