My guess

From having had a low level job in drug development. I can tell you that lots of drugs are called inhibitors because they inhibit a natural function of the body. That is how they alleviate, actually it's suppress, your symptom, kind of like covering up the red warning light on your car's dashboard. Alot of the time we would look for something that would inhibit a natural enzyme reaction in the body, which I imagine, is there for a reason. This alleviates the symptom, but it is possible you may get a whole cascade of side effects. This is why, in general, I do not think one should take a drug for a very long period of time. I learned that this one enzyme, was part of a complex cascade reaction that activated/deactivated others, each with their own function. I suppose that's probably where side effects come from. That, and the fact that you aren't addressing the true cause, whatever protective mechanism was causing it to activate in the first place.

For example, I am guessing a body is probably making excess cholesterol to protect you from something else, so does artificially lowering it really help, or is the something else worse? Or course, I'm no doctor and could be totally wrong, that's just my uneducated guess. Tweet