fatigue theory

Theory: Fatigue is related to methylation problems.

Mechanism: One product of the methylation cycle, SAM-e, is involved in energy production among other things:

SAM-e is a valuable supplement for liver detoxification as it also helps the body produce many methyl-based substances, including: carnitine. creatine phosphate (used in ATP energy production), epinephrine (adrenaline), posphatidyl choline (a nutrient that protects the nerves). Because of this SAM-e may help a variety of liver diseases, inflammatory disorders, Depression and elevated levels of homocysteine. It may also reduce intestinal inflammation and protect the brain against free radical damage.

(Modern Herbal Medicine)

When I started supplementing/dieting to address methylation my fatigue seemed to diminish.

Can anyone else reproduce this?

Let me know if you have questions on how to supplement/diet to support methylation. Tweet