I have AF and also have cadmium toxicity and have registered high with mercury and uranium in the past. Still think I could have the other too also still going on. My ND is working on my adrenals, but has me on very low levels of a zeolite with humic and fulvic acid. This is a very safe way to chelate, unlike many other forms of chelation. I had worked my way up to the highest dose he wanted me at, but the herxing/die-off became too bad, so I am back down to the lowest dose and starting over. I think until my adrenals are better I'm just going to herx like that over and over but like he said, getting the heavy metals out is imperative. I think if I stay on a low level of chelation while building up my adrenals, I should be ok. Also if you have any Amalgam fillings in your mouth, you shouldn't chelate until you have those out.