Quote: Many studies regarding myocardial ischemia and reperfusion show that leukotriene signaling may be involved in the development of ischemic injury.
They are probably wrong about the "development" part.
Probably is not evidence, it is a guess.
Leukotrienes are most likely the response to atherosclerotic injury rather than the cause of it.
Again this is a guess.
If leukotrienes are not the cause then AA isn't either.