well, since excess Iodine is excreted in 24 hours one can stop taking it for 24-48 hours and let the body settle down from the exposure. after no more than a couple of days then start right back on it. the body's reaction to it should be different to some degree or other.
upping the dose means you take enough to detox AND eliminate. many times people take enough to get toxins back in circulation but not enough to keep the toxins from depositing in a new place and causing new damage.
remember, the detox reaction to Iodine is not the Iodine itself but what iodine stirs up thats already in the body.