More on Sulfation, liver pathway

Cutler on sulfation (and salicylates)
http://onibasu.com/wiki/Sulfation_issues_and_treatment



It's a long piece of information, but a couple of things I've learned today about the sulfation pathway (Phenol sulfotransferase enzyme)...is that the other things affected by a deficiency is dopamine, seratonin, thyroid, and phytoestrogens.

Because links later don't open up, I'm going to copy/paste the info I've been reading here. The regular link wouldn't open up, I had to go to the cached page.

This stood out as I was reading it:

>>>Some recent studies indicate that salicylate has an effect on PST, an
enzyme needed by the brain and the gut to metabolize high-phenolic
compounds like the artificial colors and flavors. Salicylate
suppresses PST enzymes up to 50%. Phase II has been shown to be low
for people with ADHD or autism. Excess boron interferes with the
metabolism (breakdown and excretion) of phenols. Ritalin, used in the
treatment of ADHD, inhibits the metabolism of coumarins (phenols).
Supplementing boron reduces calcium losses by 30%, but excess boron
increases copper in the body. High copper levels reduce the vitamin
B1, and this reduces oxygen supply to the brain. Excess boron reduces
the vitamin B6 levels in the body also. Boron is found in apples,
pears, grapes, nuts, leafy green vegetables, and legumes. Supplying
these substances, especially apples, pears, and grapes, or their
juices in large amounts to PST deficient children, will cause a build
up of phenols, amines, salicylates, and other toxic substances
normally cleared by PST.

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