I'm surprised that no one has mentioned the use of supergreen foods in detoxing from heavy metals, which is a very effective way of so doing................
In addition Iodine deficiency can be remedied by the use of kelp, which is rich in this mineral.
As far as Depression is concerned, which is normally of a biochemical nature, but not always, I would try a water-fast of between 8 to 15 days.........
Jurplesman is the member to ask here within this forum with regard to the nutritional approach/treatment of depression.
I totally cured my own Major Depression thru nutritional means, and a system of living in accord with Nature..........Natural Hygiene.