Since Miracle-Mineral-Supplement works by destroying pathogens and destroying itself in the process, I don't think there is any chance of dependency. There is no accumulative behavior either. Miracle-Mineral-Supplement breaks down to sodium chloride and hydrochlorous acid within about 2 hours. I would not think the immune system organs would have a need depend upon Miracle-Mineral-Supplement . Even the pathogens will not be able to mutate. It's kill or nothing.