Hi Grizz & everyone,
I took over 800 MICROgrams of selenomethionine in divided doses throughout the day while doing the same with over 500 MILLIgrams of elemental Iodine, several years ago. I did this for several weeks and it cured my bleeding stomach ulcers. Perhaps together we can find a better answer to your question. I really believe a person needs at least 100 to 200 Micrograms of selenomethionine, or even SeMC, a day with each, 100 MILLIgrams of iodine. Keep in mind that you are probably getting some from your diet.
Some hints of too much selenium: & what are the optimal selenium amounts:
You can get toxicity issues if you consume too much selenium. The goal is to consume between 200 – 400 mcg of selenium per day. You will be getting this if you consume 1 pound (500 grams) of meat, eggs and seafood per day. If you meet these requirements, do not take any supplements of selenium. If you do not, take a supplement. Excess selenium is usually easily eliminated through sweat and urine. If you take in too much selenium, your sweat can take on a garlic-like smell.
http://mywaytoday.wordpress.com/2013/06/03/selenium-and-iodine-master-metabol...
How Much Selenium Do You Need?
The dietary supplement intake of selenium is a matter of hot debate because selenium intake has been shown to reduce cancer risk. This simple fact has gotten the public health goons involved, who typically hate vitamins and want to scare people based on their own prejudice for drugs and the profits of drug companies.
Public health officials now think that 55 mcg of selenium will raise a selenium marker in the blood, selenoprotein P, and they consider that a dose of 100 mcg is the most this particular marker needs. Taking additional selenium does not boost it further. That’s very nice, except selenoprotein P has nothing to do with thyroid function or optimal selenium status in your body.
For example, a detailed study of immunity testing doses of 50 mcg and 100 mcg found that both doses helped, especially the higher dose, but neither dose was able to optimize immune function in healthy people. The researchers suggested that higher doses of selenium would need to be tested to determine the optimal dose. Another human study showed that 200 mcg of selenium produced a better immune response than 50 mcg or 100 mcg.
A recent human study with doses of 100 mcg, 200 mcg, and 300 mcg of selenium found that as the dose increased there was a better ratio of total cholesterol to HDL Cholesterol.
A study of high dose selenium, 1,000 mcg per day and 1,500 mcg per day, in sepsis patients found that the dose was highly effective at boosting antioxidant enzymes that clear toxins. Of course, sepsis is a condition of high toxicity requiring, in theory, higher antioxidant intake, including selenium. And this dose was only for several weeks.
Even though public health officials like the idea of a range of 50 mcg – 100 mcg per day, with a safe upper limit of 400 mcg per day, they freely admit in their data that human studies with 1,600 mcg or 3,200 mcg per day did not have adverse or toxic side effects. One study in men with prostate cancer found that a dose of 800 mcg seemed to have adverse effects on PSA dynamics.
None of this safety data is trying to figure out a dose that optimizes thyroid function. This is quite unfortunate when you consider the millions of people with the problem and the potential dire health consequences for not optimizing selenium status. In the previously mentioned study showing selenium helped lower thyroid autoantibodies the dose was 80 mcg over a 12 month period.
In my clinical experience with thousands of people I find that selenium in the 200 mcg to 300 mcg range is adequate for most to improve thyroid function in a noticeable way, although some respond very well to "DOUBLE" that dose.
http://perfecthealthdiet.com/2011/05/iodine-and-hashimotos-thyroiditis-part-i/
http://www.wellnessresources.com/health/articles/seleniums_vital_role_in_thyr...
Be well,
t2t